Provided is a compound having an integrin [alpha]4 inhibiting action. A sulfonamide derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof. (In the formula, R1-R5, e-h, D, and B are as defined in the specification).本發明為提供一種具有α4整合蛋白抑制作用之化合物,其下述一般式(I)所表示之磺胺衍生物或其醫藥上所容許之鹽。(式中,R1~R5、e~h、D以及B如說明書中之記載所述)