70kD熱ショック蛋白による化合物の細胞内標的輸送

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专利权人:

ブリストル-マイヤーズ スクイブ カンパニー

发明人:

シェリ・エム・フジハラ,スティーブン・ジー・ナドラー

申请号：

JP2000583940

公开号：

JP4892132B2

申请日:

1999.11.17

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

The present invention provides a carrier for the delivery of molecules with biological function into both cellular and nuclear compartments. The carrier disclosed is heat shock protein 70 ("Hsp70"), or a fragment of Hsp70 as described herein, as a vehicle for directed, non-invasive delivery of molecules, such as proteins, peptides, or DNA, that may modulate cellular activity. The present invention also encompasses the use of Hsp70, or a fragment thereof, to modulate cellular activity, preferably to modulate nuclear activity in a cell or cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/