The present invention relates to compositions and methods relating to chimeric antigen receptor (CAR) polypeptides and methods relating thereto. In one embodiment, the present invention relates to engineered cells having chimeric antigen receptor polypeptides directed to at least two targets. In another embodiment, the present invention relates to engineered cells having chimeric antigen receptor polypeptides and an enhancer moiety.本發明係關於與嵌合抗原受體(CAR)多肽相關之組合物及方法，以及與其有關之方法。在一個實施例中，本發明係關於經工程改造之細胞，其具有針對至少兩個標靶之嵌合抗原受體多肽。在另一實施例中，本發明係關於經工程改造之細胞，其具有嵌合抗原受體多肽及強化子部分。
