SEO, In Yong,서인용,JANG, Seon Ho,장선호,KOO, Song Hee,구송희,KIM, Chan,김찬,LEE, Seoung Hoon,이승훈
申请号：
KRKR2017/005423
公开号：
WO2017/204563A1
申请日:
2017.05.24
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
Provided is a yarn for a cell culture support. The yarn according to an embodiment of the present invention includes a plurality of twisted monofilament strands, wherein at least a portion of the plurality of twisted monofilament strands are untwisted such that spaces are formed between the monofilament strands in order to prevent density-dependent inhibition of cultured cells and increase a specific surface area for cell contact. Accordingly, as a microenvironment yarn appropriate for the movement, proliferation, and differentiation of cells being cultured is realized, the cell proliferation rate and cell survival rate can be enhanced. Also, as a space for cell proliferation is maximally realized in a limited space in the support, a large amount of cells can be simultaneously cultured, and, because phenomenon of the suppression of cell proliferation due to contact between cells is prevented, cell proliferation can steadily continue. Furthermore, cells cultured through the yarn can be cultured in a shape/structure that is more appropriate for being applied to an in vitro experimental model or being implanted in the body of an animal, and can be widely applied in various products used in cell culturing fields or tissue engineering fields such as bioreactors, cell culture containers, or kits for implantation in a body.L'invention concerne un fil pour un support de culture cellulaire. Le fil selon un mode de réalisation de la présente invention comprend une pluralité de brins de monofilament torsadés, au moins une partie de la pluralité de brins de monofilament torsadés n'étant pas torsadée de telle sorte que des espaces sont formés entre les brins de monofilament pour empêcher une inhibition, dépendante de la densité, de cellules en culture et augmenter une surface spécifique pour un contact cellulaire. En conséquence, étant donné qu'un fil de micro-environnement approprié pour le mouvement, la prolifération et la différenciation de cellules en culture est réalisé, le
