GEOFFREY C. WINTERS,ALEXANDER LAURENCE MANDEL,JAMES R. RICH,BRADLEY JOHN HEDBERG,TOM HAN HSIAO HSIEH,ELYSE MARIE JOSÉE BOURQUE,JOHN BABCOOK
申请号：
PT14763699
公开号：
PT2968440T
申请日:
2014.03.14
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
