Gudbjartsson Daniel,Bjornsdottir Unnur Steina,Sulem Patrick
申请号：
US201514747929
公开号：
US2016319351(A1)
申请日:
2015.06.23
申请国别(地区):
美国
年份:
2016
代理人:
摘要：
Polymorphic variants (e.g., certain alleles of polymorphic markers) that have been found to be associated with high blood eosinophil counts, conditions causative of eosinophilia (e.g., asthma, myocardial infarction), and/or hypertension are provided herein. Such polymorphic markers are useful for diagnostic purposes, such as in methods of determining a susceptility, and for prognostic purposes, including methods of predicting prognosis and methods of assessing an individual for probability of a response to a therapeutic agent, as further described herein. Further applications utilize the polymorphic markers of the invention include, screening methods and genotyping methods. The invention furthermore provides related kits, computer-readable medium, and apparatus.
