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PEPTIDE IMMUNOMODULATEUR
专利权人:
POSCO;POSTECH FOUNDATION
发明人:
RYU, SUNG-HO,SUH, PANN-GHILL,BAE, YOE-SIK,SONG, JI-YOUNG
申请号:
CA2446872
公开号:
CA2446872C
申请日:
2003.01.28
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Disclosed are peptides having SEQ ID NOs: 1 to 24 that induce superoxidegeneration by human monocytes or neutrophils; that induce an intracellularcalcium increase by human peripheral blood monocytes or neutrophils; binds toformyl peptide receptor or formyl peptide receptor-like 1; that inducechemotactic migration of human monocytes or neutrophils in vitro; that inducedegranulation in formyl peptide receptor expressing cells or formyl peptidereceptor-like 1 expressing cells; that stimulate extracellular signalregulated protein kinase phosphorylation via activation of formyl peptidereceptor or formyl peptide receptor-like 1; or that stimulate Aktphosphorylation via activation of formyl peptide receptor or formyl peptidereceptor-like 1.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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