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Amino acid compounds and methods of use
专利权人:
Inc.;Pliant Therapeutics
发明人:
David John Morgans, Jr.,Randall L. Halcomb,Gustave Bergnes,Hui Li,Lan Jiang,Jacob Cha,Timothy Hom
申请号:
US16471521
公开号:
US10696672B2
申请日:
2017.12.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to compounds of formula (I): formula (I) or a salt thereof wherein R1, R5, R7, R8, X, m, n, p and q are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are αvβ6 integrin inhibitors that are useful for treating tissue specific fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).
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