Gary Fujii,Francis C. Szoka, Jr.,Douglas S. Watson
申请号:
US15181028
公开号:
US09931419B2
申请日:
2016.06.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to liposomal vaccine compositions, methods for the manufacture thereof, and methods for the use thereof to stimulate an immune response in an animal. These compositions comprise dimyristoylphosphatidylcholine (“DMPC”) either dimyristoylphosphatidylglycerol (“DMPG”) or dimyristoyltrimethylammonium propane (“DMTAP”) or both DMPC and DMTAP and at least one sterol derivative providing a covalent anchor for one or more immunogenic polypeptide(s) or carbohydrate(s).