A device for making an incision in the tympanic membrane, withdrawing fluid from the tympanic cavity and administering a medicament to the space behind the tympanic membrane is provided. The device has a barrel-shaped casing (1) having a rotatable end turret (38). A first trigger (2) allows a shaft (18) to pierce the tympanic membrane and a tubular vacuum cartridge (32). The cartridge allows aspiration of fluid. A second trigger (4) causes medicament (34) to be released into the space behind the tympanic membrane.