GARCIA ANTON, José María,ALMINANA DOMENECH, Nuria,FERRER MONTIEL, Antonio Vicente
申请号：
ES12710106
公开号：
ES2600852T3
申请日:
2012.03.23
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A peptide of the general formula (I) R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2 (I) its stereoisomers, mixtures thereof and / or their cosmetically or pharmaceutically acceptable salts , characterized in that: AA1 is selected from the group consisting of -His- and -Ser- identified by the formula ** Formula ** AA2 is selected from the group consisting of -Ile- and -Val-； AA3 is selected from the group consisting of -Tyr- identified by the formula ** Formula ** and-Val-； AA4 is -Val-； AA5 is selected from the group consisting of -Ala-, -Arg- and -Gly-； AA6 is selected from the group consisting of -Thr- and -Val-； W, X, Y and Z are amino acids and are independently selected from each other； n, m, p and q are independently selected from each other and have a value of 0 or 1； n + m + p + q is less than or equal to 2 R1 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroaryl alkyl, aryl substituted or unsubstituted, substituted or unsubstituted aralkyl and R5-CO-, wherein R5 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted aryl, aralkyl substituted or unsubstituted, substituted or unsubstituted heterocyclyl and substituted or unsubstituted heteroarylalkyl； R2 is selected from the group consisting of -NR3R4, -OR3 and -SR3, in which R3 and R4 are independently selected from the group consisting of H, substituted or unsubstituted aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl substituted, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted aralkyl； and with the proviso that R1 and R2 are not α-amino acids.Un péptido de fórmula general (I) R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2
