Toki, Brian E.,Senter, Peter D.,Doronina, Svetlana
申请号:
AU2010201459
公开号:
AU2010201459B2
申请日:
2010.04.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2010201459B220121206.pdf#####ABSTRACT Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptidebased Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug compounds are also disclosed. Methods for treating cancer, an autoimmune disease or an infectious disease using the compounds and compositions of the invention are also disclosed.