KIM, HYUN KEE,CHUNG, JUNHO,KIM, MIN SOO,YOON, SOO MIN
申请号:
EP13760897
公开号:
EP2826790A4
申请日:
2013.03.15
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to a Gremlin-1 antibody that inhibits Gremlin-1 in a manner independent of bone morphogenetic protein (BMP) or vascular endothelial growth factor receptor-2 (VEGFR-2), thus providing the effect of treating cancer. The antibody of the present invention inhibits cell migration, cell invasion and cell proliferation which are dependent on Gremlin-1, and therefore, can be effectively used in treating cancer or immune disease.