Ihor R. Lemischka,Kateri Moore,Carlos Filipe Pereira
申请号：
US14374639
公开号：
US09540612B2
申请日:
2013.01.30
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The disclosure relates to the development of methods for making hematopoietic stem cells from differentiated cells by introducing and expressing transcription factors. More particularly, the disclosure provides methods for redirecting differentiated cells to a hematopoietic stem cell state or to a hemogenic endothelial cell state by direct programming with specific combinations of transcription factors.
