MIKITA, THOMAS,ELY, LAUREN K.,GAO, HUILAN,KIM, YUN,RONDON, ISAAC J.,DAVID, TOVO,COUGHLIN, SHAUN R.
申请号：
CA3025896
公开号：
CA3025896A1
申请日:
2016.07.22
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
In one aspect, antibodies, or antigen-binding fragments thereof, that specifically bind to activated Factor XI (FXIa) are provided. Also provided are methods of obtaining such antibodies and nucleic acids encoding the same. In another aspect, compositions and therapeutic prevention of thrombotic diseases, disorders or conditions are provided. In another aspect, anti-idiotype antibodies that bind anti-FXIa antibodies of the disclosure, as well as compositions comprising the anti-idiotype antibodies, methods of obtaining the antibodies and nucleic acids encoding the same, are also provided.
