The invention relates to a method for the decontamination and disinfection of a transport vehicle, and device for controlling said decontamination. The method according to the invention comprises at least one heat treatment phase of the vehicle body or of at least one compartment of the body intended for transportation, injecting a hot gas into same at a temperature that guarantees the elimination of the pathogens, said temperature being between 0ºC and 91ºC. The device for controlling the decontamination comprises: a control unit (1); a user interface (2); a series of conveniently distributed temperature sensors (3); and a memory (5) for the storage of data relating to dates, temperatures and other variables relating to the decontaminations carried out, as well as the identification of the vehicle on which the decontamination process is carried out.