The Invention relates to a Pharmaceutical composition comprising (1) an Extruded Solid dispersion comprising (R) - 2 - (1 - (3 - amino - 4 - 5 - cloropirimidina carboxamido) ethyl) - N - (4 - 5 - Chloro - (trifluoromEthyl) pyridine - 2 - il) thiazole-5-carboxamide or a pharmaceutically acceptable Salt thereof and a vinilpirrolidinona - vinyl acetate Copolymer and (2) one or more pharmaceutically acceptable excipientsFor the treatment of Cancer and a process for its preparation.The Invention also relates to the Administration of the pharmaceutical composition to a patient under an intermittent dosing regimenLa invencion se refiere a una composicion farmaceutica que comprende (1) un extruido de dispersion solida que comprende (R)-2-(1-(6-amino-5-cloropirimidina-4-carboxamido)etil)-N-(5-cloro-4-(trifluorometil)piridina-2-il)tiazol-5-carboxamida o una sal farmaceuticamente aceptable del mismo y un copolimero de acetato de vinilpirrolidinona-vinilo y (2) uno o mas excipientes farmaceuticamente aceptables, para el tratamiento de cancer y un proceso para su preparacion. la invencion tambien se refiere a la administracion de la composicion farmaceutica a un paciente segun un regimen de dosificacion intermitente