The present application provides a device for the simultaneous or the separate perfusion and occlusion of a vessel comprising a body having a distal end, a proximal end, a single lumen (66, 80) extending between the proximal end and the distal end, and at least one opening (63,72) which is in fluid communication with the lumen for delivering a therapeutic treatment to a vessel and at least one expandable balloon (65,70,81) coupled with the body of the device, said balloon is provided with an interior which is in fluid communication with the lumen of the device through at least one opening (68, 69, 70), said opening is provided with at least one valve (71) which is movable from a closed position, in which fluid communication of the lumen with the interior of the balloon is prevented, to an open position in which the lumen is in fluid communication with the interior of the balloon.