This invention provides: 1) a method of treating a subject suffering from a muscle wasting disorder 2) a method of preventing a muscle wasting disorder in a subject 3) a method of treating, preventing, suppressing, inhibiting or reducing muscle loss in a subject suffering from a muscle wasting disorder 4) a method of treating, preventing, inhibiting, reducing or suppressing muscle wasting in a subject suffering from a muscle wasting disorder and/or 5) a method of treating, preventing, inhibiting, reducing or suppressing muscle protein catabolism in a subject suffering from a muscle wasting disorder, by administering to the subject a selective androgen receptor modulator (SARM) and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide or any combination thereof, as described herein.本發明提供:(1)一種治療病人肌肉耗損症的方法,(2)一種預防病人肌肉耗損症的方法,(3)一種治療、預防、壓制、抑制或減少肌肉耗損症的病人肌肉喪失之方法,(4)一種治療、預防、抑制、減少或壓制肌肉耗損症的病人肌肉耗損之方法,與/或(5)一種治療、預防、抑制、減少或壓制肌肉耗損症的病人肌肉蛋白質異化作用之方法,其係施與病人選擇性雄性激素受體調控子(SARM)與/或其類似物、衍生物、異構物、代謝物、醫葯可接受的鹽、醫葯產物、水合物、N-氧化物或其任何如本文所述之組合。(無元件符號說明)