PETTERSSON, KNUT;FROSTEGARD, JOHAN;ATHERA BIOTECHNOLOGIES AB
发明人:
FROSTEGARD, JOHAN,PETTERSSON, KNUT
申请号：
CA2708956
公开号：
CA2708956C
申请日:
2008.12.18
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to a method for the treatment of vasculardysfunction, reducing ischemic pain and/ortreatment of a vascular disease comprising administering a therapeuticallyeffective amount of Annexin A5 or a functional analogueor variant thereof to a patient in need of such treatment. The vasculardysfunction, ischemic pain and/or vascular disease may beassociated with impaired endothelium mediated vasodilatation, a reduced eNOSactivity, and/or a reduced NO bioavailability. Thepatient may be suffering from a disease selected from angina pectoris,ischemic heart disease, peripheral artery disease, systolichypertension, migraine, type 2 diabetes and erectile dysfunction.
