Derives d'acide 3-[2-(3-amino-2-oxo-2H-pyridin-1-yl) acetylamino]-4-oxo-pentanoique et leur utilisation comme inhibiteurs de caspase

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

申请号：

EP11183025.3

公开号：

EP2412707A2

申请日:

2004.05.27

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention provides a compound of formula I:wherein R1, R2, R3, R4, and R5 are as defined herein. The present invention also provides pharmaceutical compositions and methods using such compositions for treating a caspase-mediated diseases and processes for preparing the compounds of the invention.

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