Provided herein is a curable sealer for use in sealing a canal wall in a rootcanal treatment orretreatment procedure, including an adhesive compound having a cytotoxicitysufficiently low as tobe suitable for use in the root canal procedure; and a flowability of at least46 mm at 23° Celsius.Provided herein are uses of the sealer for sealing a canal wall. Also providedis a curable sealer foruse in sealing a canal wall in a root canal treatment or retreatmentprocedure, including an adhesivecompound having: a cytotoxicity sufficiently low as to be suitable for use inthe root canal procedure;and a flowability at 23° Celsius about equal to the flowability ofwater. Provided herein are uses ofthe sealer for sealing a canal wall.