A compound having the structurewherein R is an angiotensin receptor antagonist active group, and Y is1) —(CH2)3R5,2) —C(O)(CH2)2R5,3) —C(R1R2)OC(O)O(CH2)nR5, wherein n is 1 or 2,4) —C(R1R2)OC(O)CH2CH2R5,5) —C(R1R2)OC(O)OCH2CH2C(R3R4)R5,provided that when Y is —C(O)(CH2)2R5, then R isR1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-4 alkyl R5 is —CH(ONO2)CH(ONO2)R6 R6 is selected from CH3, CH2CH3 and CH(CH3)2or a pharmaceutically acceptable salt or hydrate thereof, which is useful for treating hypertension.
