The invention discloses a kind of six-dimensional lecithoid soft capsule preparation method,Step includes: the bulk pharmaceutical chemicals for taking following weight parts: 1-100 parts of soybean lecithin powder,5-120 parts of soybean oil,2-8 parts of niacinamide,.5-2 parts of vitaminB10,0.5-2 parts of vitamin B2,0.5-2 parts of vitamin B6,0.5-2 × 10-3 parts of vitamin B12 and 0.5-2 parts of vitamin E,It is spare； Bulk pharmaceutical chemicals are added and are stirred evenly by certain first Hou sequence； Above-mentioned admixing medical solutions are subjected to colloid mill milled processed,Vitamin E is added in stirring,It stirs evenly,Content medical fluid needed for obtaining； Take above content object medical fluid that required soft capsule is prepared according to common process. Bulk pharmaceutical chemicals in the preparation method by raw material with soybean lecithin powder and soybean oil by being replaced preparing soft capsule by raw material of liquid phosphatide in the prior art, the six-dimensional lecithoid soft capsule of acquisition more homogeneous, not stratified, the significant effect for having long-time stability good.本發明公開了一種六維磷脂軟膠囊製備方法，步驟包括：取下述重量份的原料藥：大豆磷脂粉1-100份、大豆油5-120份、烟酰胺2-8份、維生素B10.5-2份、維生素B20.5-2份、維生素B60.5-2份、維生素B120.5-2×10-3份及維生素E0.5-2份，備用；將原料藥按一定先後順序加入並攪拌均勻；將上述混合藥液進行膠體磨研磨處理，攪拌加入維生素E，攪勻，得所需內容物藥液；取上述內容物藥液按照常規工藝製備得到所需的軟膠囊。所述製備方法中的原料藥通過以大豆磷脂粉和大豆油爲原料代替現有技術中以液態磷脂爲原料製備軟膠囊，獲得的六維磷脂軟膠囊更加均質、不分層，具有長期穩定性好的顯著效果。
