A medical information processing apparatus includes processing circuitry. The processing circuitry is configured to acquire medical image data representing a blood vessel of a subject, extract a blood vessel shape from the medical image data, determine degree of meandering in each of regions from the extracted blood vessel shape, specify a deformed region in which the degree of meandering changes due to insertion of a device into the blood vessel on the basis of the degree of meandering, and output the deformed region in the blood vessel.