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COMPOSITION
专利权人:
Rebio Technologies Oy;Rebio Technologies Limited;Rebio Technologies Limited
发明人:
Jonathan Glen,Harri Jukarainen,Jukka Tuominen
申请号:
US16765297
公开号:
US20200283568A1
申请日:
2018.11.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein is a bioresorbable polyester wherein the metal content of the polyester is >;0 ppm and <;40 ppm, a controlled release pharmaceutical composition containing such polyesters, and a kit for injecting a controlled release pharmaceutical composition. Also provided herein is a method of purifying a bioresorbable polyester with a metal content >;0 ppm comprising the steps of: i) dissolving the polyester in an organic solvent to form a polyester-solvent solution, wherein the organic solvent comprises at least one heteroatom selected from oxygen, nitrogen, sulphur and phosphorus; ii) precipitating the polyester from the polyester-solvent solution by combining the polyester-solvent solution with an organic non-solvent, said non-solvent being an alcohol; and (iii) separating the precipitated polyester from the solvent and non-solvent to obtain a purified polyester.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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