DOUBLE INHIBITEURS DE VOIES TIM-3 ET PD-1

• 收藏
• 分享

专利权人:

AURIGENE DISCOVERY TECHNOLOGIES LIMITED

发明人:

SASIKUMAR, POTTAYIL GOVINDAN NAIR,RAMACHANDRA, MURALIDHARA,NAREMADDEPALLI, SEETHARAMAIAH SETTY SUDARSHAN,GOWDA, NAGARAJ

申请号：

CA3080098

公开号：

CA3080098A1

申请日:

2018.10.31

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present disclosure relates to 3-substituted 1,2,4-oxadiazole compounds and their derivatives, which are useful as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3) inhibitors or as dual inhibitors of TIM-3 and the programmed cell death 1 (PD-1) signaling pathway. The disclosure also relates to treatment of disorders by inhibiting an immunosuppressive signal induced by TIM-3, PD-1, PD-Ll, and/or PD- L2.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/