An orthodontic self-locking bracket includes a bracket body having an arch wire bracket slot and a bracket cover matched with the bracket body. Two sides of the arch wire bracket slot are provided with work wings. A bracket opening is arranged at the intersection of the arch wire bracket slot on the bracket body, and the bracket cover is inserted into the bracket opening and is in sliding fit with the bracket body. Left side of the arch wire bracket slot is provided with a pin shaft penetrating through the bracket opening, and the pin shaft is in clamping fit with the lower part of the bracket cover, so that the arch wire bracket slot can be closed and opened by the bracket cover. The bracket is locked and unlocked only by sliding rather than overturning the bracket cover. Complex operation for ligaturing a steel wire is eliminated.