Samuel C. Wagner,Thomas E. Ichim,Vladimir Bogin,Boris Minev
申请号：
US15158476
公开号：
US20170021002A1
申请日:
2016.05.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed are protocols, procedures and therapeutic compositions useful for augmentation of immunity to cancer and cancer associated endothelial cells by treatment with histone deacetylase (HDAC) inhibitors capable of augmenting stimulatory and costimulatory molecules on said cancer vaccines. Additionally, the invention teaches specific concentrations of HDAC inhibitors useful for stimulation of in vivo immunity to tumor and tumor endothelial cell targeting vaccines.
