Andrea Carfi,Sumana Chandramouli,Ethan C. Settembre
申请号：
US15533483
公开号：
US10364273B2
申请日:
2015.12.07
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention generally relates to recombinant human cytomegalovirus (CMV) gB proteins and immunogenic fragments thereof, which do not comprise a transmembrane (TM) domain； and comprise one or more mutations that reduce the aggregation between the monomeric trimers of gB, and/or adhesion of the monomeric trimer of gB to the host cell.
