PEREZ, Heidi L.,WEI, Donna D.,BORZILLERI, Robert M.,GANGWAR, Sanjeev,SCHROEDER, Gretchen M.,CHENG, Heng,SCHMIDT, Robert J.
申请号:
ES15805337
公开号:
ES2719756T3
申请日:
2015.11.10
申请国别(地区):
ES
年份:
2019
代理人:
摘要:
Tubulysin analogs of the formula (I) where R1, R2 R3, R4, R5, R6, R7, and Y are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety.