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PROCESSO PARA A PREPARAÇÃO DE INIBIDORES DO METABOLISMO DOS NUCLEÓSIDOS
专利权人:
VICTORIA LINK LIMITED;ALBERT EINSTEIN COLLEGE OF MEDICINE, INC
发明人:
VERN L. SCHRAMM,RICHARD HUBERT FURNEAUX,PETER CHARLES TYLER
申请号:
PT09150953
公开号:
PT2077268T
申请日:
2000.04.07
申请国别(地区):
PT
年份:
2017
代理人:
摘要:
The invention provides a compound of the formula: wherein Y is an unsubstituted or substituted alkyl or arylalkyl group having 1 to 8 carbon atoms, as well as a process of preparing said compound. The invention also provides a process of preparing the compound 3H,5H-pyrrolo[3,2-d]pyrimidin-4-one, comprising the step of reacting a compound of the formula (A) defined above with a reagent capable of delivering a formyl equivalent. The invention also provides a process of preparing the compound 2-amino-3 H ,5 H -pyrrolo[3,2- d ]pyrimidin-4-one, comprising the step of reacting the compound 2-(N-dimethylaminomethylene)amino-6-(2-dimethylaminovinyl)-5-nitropyrimid-4-one with a reagent capable of reducing the nitro group, to produce the compound 2-amino-3 H ,5 H- pyrrolo[3,2- d ]pyrimidin-4-one.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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