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use of propylene glycol as the sole solvent and excipient for the formulation of medicinal products with active ingredients less than 500 mole and soluble in propylene glycol and more specifically the use of the active ingredients isotretinoin, potassium diclofenac, tamoxifen citrate, exemestane, finasteride, estradiol, didrogesterone and estriol for the specific composition of seven transdermal drugs using propylene glycol as a solvent and excipient qsp
专利权人:
MARIO VIRGILIO DE CARVALHO JUNIOR
发明人:
MARIO VIRGILIO DE CARVALHO JUNIOR
申请号:
BR102017024822
公开号:
BR102017024822A2
申请日:
2017.11.20
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
use of propylene glycol as the sole solvent and excipient for the formulation of medicinal products with active ingredients less than 500 mole and soluble in propylene glycol and more specifically the use of the active ingredients isotretinoin, potassium diclofenac, tamoxifen citrate, exemestane, finasteride, estradiol, didrogesterone and estriol for the specific composition of seven transdermal drugs using propylene glycol as a solvent and excipient qsp. The field of application is the pharmaceutical industry for transdermal drug formulations. use of isotretinoin (1), potassium diclofenac (2), tamoxifen citrate (3), tamoxifen citrate and exemestane (4) finasteride (5) estradiol + didrogesterone (6) estriol (7) for the production of seven transdermal formulations characterized by using propylene glycol as the sole solvent and excipient qsp. as well as the use of propylene glycol as the sole solvent and excipient qsp for transdermal drug formulations in compositions which use propylene glycol as a solvent and excipient qsp in a percentage of 80% to 100% of qsp without the use of hydroalcohol gels and creams.utilização do propilenoglicol como único solvente e excipiente qsp para formulação de medicamentos com princípios ativos com massa molar inferior a 500 e solúveis em propilenoglicol e mais especificamente a utilização dos princípios ativos isotretinoína, diclofenaco de potássio, citrato de tamoxifeno, exemestano, finasterida, estradiol, didrogesterona e estriol para a composição específica de sete medicamentos transdérmicos utilizando o propilenoglicol como solvente e excipiente qsp. o campo de aplicação é a indústria farmacêutica para área de formulações medicamentosas via transdérmica. utilização dos fármacos isotretinoína (1), diclofenaco de potássio (2), citrato de tamoxifeno (3), citrato de tamoxifeno e exemestano (4) finasterida (5) estradiol + didrogesterona (6) estriol (7) para produção de sete formulação transdérmica caracterizadas por utilizar o propilen
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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