Helen Jane SZEKERES,Maria Ann WHATTON,Andrew Caerwyn WILLIAMS
申请号:
US16781148
公开号:
US20200247752A1
申请日:
2020.02.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Small molecule potentiatiors to potassium channels (such as Kv7 potentiators—;which are also called KCNQ potentiators), compositions including such compounds, and methods of using such compounds for the treatment of Amyotrophic Lateral Sclerosis and other neurological diseases caused by changes in motor neuron excitability, including, but not limited to, primary lateral sclerosis, pseudobulbar palsy, progressive bulbar palsy, progressive muscular atrophy and epilepsy.