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Pyrimidine and triazine sulfonamide derivatives as bradykinin B1 receptor (B1R) inhibitors for the treatment of pain.
专利权人:
GRUENENTHAL GMBH
发明人:
SCHUNK, STEFAN,REICH, MELANIE,HENNIG, KAMILA,ENGELS, MICHAEL,GERMANN, TIENO,JOSTOCK, RUTH,HEES, SABINE
申请号:
DK09740860
公开号:
DK2356101T3
申请日:
2009.10.22
申请国别(地区):
DK
年份:
2013
代理人:
摘要:
Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.
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