A PROCESS FOR PREPARATION OF A NOVEL COMPOUND 7-(4-HYDROXY-9,10-DIHYDROANTHRACEN-2-YL)-3-METHYLHEPT-2-ENOIC ACID FROM CASSIA AURICULATA LINN. STEM BARK WITH ANTIDIABETIC ACTIVITY
A process for preparation of novel compound of 7-(4-hydroxy-9,10 dihydroanthracen-2-yl)-3-methylhept-2-enoic acid with antidiabetic activity comprising steps of:- 7-(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl)-3-rnethylhept-2-enoic acid Molecular formula: C22H20O5 Formula Weight: 364.3912 a) Cassia auriculata stem bark powder (2kg) was completely extracted with methanol. b) 40 g of methanol extract was subjected to column chromatography and 146 fractions were collected. The collected fractions wre combined based on the TLC spot to get major fractions. d) The fractions 117-146 was rechromatographed and fractions 61-70 formed a new compound, which was studied using spectroscopic techniques and structure of compound was confirmed as 7-(4-hydroxy-9,10 dihydroanthracen-2-yl)-3-methylhept-2-enoic acid.
