The present invention provides a large bag with a cold-keeping function, comprising a large body bag and a plurality of cold-preserving materials, the bag has a bottom layer and a cover layer and a joint member, and an accommodation space is formed between the bottom layer and the cover layer. The binding member can close the accommodating space, and the general bag is provided with a plurality of accommodating pockets, and the chilling materials are respectively disposed in the accommodating pockets.本創作提供一種具有保冷功能之大體袋,包含一大體袋及複數保冷材料,該大體袋具有一底部層及一覆蓋層及一結合件,該底部層及該覆蓋層之間形成一容置空間,該結合件能封閉該容置空間,該大體袋內設有複數容置袋,該些保冷材料分別設置於該些容置袋內。