Stefan Ewert,Adrian Auf Der Maur,Susann Cattepoel,Roger Nitsch
申请号：
US12677732
公开号：
US08323647B2
申请日:
2008.09.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention discloses an isolated antibody that selectively binds to the C-terminal part of Abeta and is humanized or fully human. The antibody of the invention is capable of preventing oligomerization of Abeta. Furthermore, a method of diagnosis comprising the steps of: (i) Labelling an antibody (ii) Administering an effective dose of said antibody intranasally or systemically to a subject and (iii) Detecting the concentration and/or presence of the labelled antibody in body parts of the subject is disclosed.
