The present invention discloses the use of therapeutic and preventive action of L-3-n-butylphthalide on the cerebral infarct induced by ischemic cerebral stroke. The molecular formula is shows as follows:本發明公開了如通式(I)所示左旋丁基苯酞在製備預防和治療腦梗塞的藥物的應用,尤其是局部腦缺血導致的腦梗塞。