Laboratoire Français du Fractionnement et des Biotechnologies
发明人:
Chtourou, Abdessatar,Dhainaut, Frédéric,Paolantonacci, Philippe
申请号：
ES20110162751T
公开号：
ES2690664(T3)
申请日:
2006.12.26
申请国别(地区):
西班牙
年份:
2018
代理人:
摘要：
Immunoglobulin G (IgG) concentrate for therapeutic use, comprises anti-A and anti-B antibodies compliant with a negative result in the indirect Coombs test in vitro. An independent claim is included for obtaining the IgG concentrate comprising preparing an IgG concentrate by ethanolic fractionation and/or chromatographic separation, in association with a viral inactivation, immunoaffinity chromatography by percolation of the IgG concentrate on a support mixture of which matrices are grafted with oligosaccharide groups antigenically similar to blood groups A and B, and filtering for elimination of virus and/or particles of size higher than 20 nm. ACTIVITY : Antimicrobial; Immunosuppressive. MECHANISM OF ACTION : None given.
