biarylcarboxyarylamides as type 1 vanilloid receptor modulators, pharmaceutical composition comprising them and use of said compounds in the preparation of medicaments
PIER GIOVANNI BARALDI,PIER ANDREA BOREA,PIERANGELO GEPPETTI,MARIA GIOVANNA PAVANI,FRANCESCA FRUTTAROLO,MARCELLO TREVISAN
申请号：
BRPI0713988
公开号：
BRPI0713988A2
申请日:
2007.07.02
申请国别(地区):
BR
年份:
2012
代理人:
摘要：
BIARYL CARBOXYARYLAMIDS AS MODULATORS OF THE VANILLA TYPE 1 RECEPTOR, PHARMACEUTICAL COMPOSITION UNDERSTANDING THE SAME AND USE OF THE REFERRED COMPOUNDS IN THE PREPARATION OF MEDICINES. The present invention relates to compounds of formula (I): in which A and Z are as defined in the description, together with methods for preparing such derivatives and their use for the treatment of inflammatory diseases such as neuropathic pain.BIARILCARBOXIARILAMIDAS COMO MODULADORES DO RECEPTOR VANILàIDE TIPO 1, COMPOSIÇçO FARAMCÊUTICA COMPREENDENDO AS MESMAS E USO DOS REFERIDOS COMPOSTOS NA PREPARAÇçO DE MEDICAMENTOS. A presente invenção refere-se a compostos de fórmula (I): na qual A e Z são conforme definidos na descrição, juntamente com métodos para preparação de tais derivados e seu uso para o tratamento de doenças inflamatórias tal como dor neuropática.
