Yossef Raviv,Julie M. Belanger,Mathias Viard,Robert Blumenthal,Julian W. Bess, Jr.
申请号:
US12847231
公开号:
US08613934B2
申请日:
2010.07.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention involves inactivation of viral populations by treating the viral populations with a compound to crosslink proteins in the viral membrane, UV irradiation and further inactivation of the viruses using detergent(s). According to the invention, this method preserves the native structure of viral epitopes so that the inactivated viral preparations can be used in immunological compositions that will inhibit and/or prevent viral infection when administered to an animal.