A system for cooling or heating at least a portion of a patient's body, comprising: (a) an esophageal heat transfer device (200； 300) that includes: (i) a plurality of lumens (224, 226； 320 , 322； 406, 408； 510, 512), a lumen of the supply tube of the heat transfer medium (224； 320； 406； 510) of a supply tube of the heat transfer medium (218； 310； 402 ； 502； 608) and a lumen of the return tube of the heat transfer medium (226； 322； 408； 512) of a return tube of the heat transfer medium (222； 312； 404； 504； 610), configured to provide a fluid path for the flow of a heat transfer medium； (ii) a proximal end (204； 302) that includes an inlet port of the heat transfer medium (120； 208； 308； 414) and an outlet port of the heat transfer medium (122； 210； 314； 416)； (iii) a distal end (202； 306) configured for insertion into a patient's esophagus； (iv) at least one semi-rigid tube (206； 304) extending between said proximal end (204； 302) and said distal end (202； 306)； said at least one semi-rigid tube (206； 304) defining said lumen of the supply tube of the heat transfer medium (224； 320； 406； 510) and said lumen of the return tube of the heat transfer medium (226 ； 322； 408； 512)； (v) a heat transfer region configured to contact the esophageal epithelium of a patient； (b) a supply line connected to said input port (120； 208； 308； 414)； and (c) a return line connected to said output port (122； 210； 314； 416)； characterized in that said return tube of the heat transfer medium (222； 312； 404； 504； 610) is placed inside said supply tube of the heat transfer medium (218； 310； 402； 502； 608)； and said heat transfer region has a surface area of at least about 100 cm2； wherein said esophageal heat transfer device (200； 300) is capable of cooling a mass at a speed of about 350 kJ / h to about 530 kJ / h； and wherein said esophageal heat transfer device (200； 300) is not an esophageal balloon-type heat transfer device.Un sistema para enfriar o calentar al menos una porción del cue
