To attach an ear tag (6, 10) to an ear (16) and to remove a sample (22) containing tissue of the ear therefrom, a mandrel (8), which is fastened to a mandrel region (6) of the ear tag, is brought by means of pliers (1) on a first movement path through the ear (16) into a hole (12) formed in a hole part (10) of the ear tag and anchored there, while the sample (22) is taken with the aid of a removal head (17) and is brought out of engagement with the hole (12) by interaction with the mandrel (8) with a movement component oriented transversely to the first movement path, before the mandrel (8) is anchored in said hole.