Arap, Wadih,Rotolo, Jimmy,Pasqualini, Renate,Kolesnick, Richard
申请号：
AU2008247368
公开号：
AU2008247368B2
申请日:
2008.05.06
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
We have discovered that administering anti-ceramide antibody treats and preventsan array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killingand by damage to endothelial microvasculture, including radiation-inducedGI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmunediseases. We have also discovered new anti-ceramide monoclonal antibodies,that have therapeutic use preferably in humanized form to treat or prevent thesediseases.
