The invention relates to an auto-injector with a base housing (2), a carpule (6), a needle arrangement (7), at least one drive assembly (8) and a securing assembly (9) which secures the drive assembly (8) in its position with respect to the base housing (2) until activated for the injection procedure. The securing assembly (9) comprises a securing cap (12) with a cap jacket (14), a cap wall (15) and a securing pin (16) arranged inside the cap jacket (14). Arranged between the securing cap (12) and the base housing (2) is a guide arrangement (17) with a first and a second guide element (19, 20) which define an adjustment path (18) delimited in the axial direction on the side directed away from the distal end (3). In its release position, the securing cap (12) is still arranged and held on the base housing (2).
