Roland Greinwald,Ralph Mueller,Markus Proels,Rudolf Wilhelm
申请号：
US15833428
公开号：
US10369100B2
申请日:
2017.12.06
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
