METHOD FOR THE PREPARATION OF 1-BENZOTRIAZOLYL CARBONATE ESTERS OF WATER SOLUBLE POLYMERS.

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专利权人:

发明人:

申请号：

EP00986602.1

公开号：

EP1259563B2

申请日:

2000.12.18

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention provides a biologically active conjugate, obtainable by reacting an amino acid derivative of the following structure wherein PEG is poly(ethylene glycol) and Z is selected from the group consisting ofH, N-succinimidyl, or 1-benzotriazolyl, with a protein.

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