Solution phase synthesis and crystallization of beta-turn peptidomimetic cyclic salts

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专利权人:

Mimetogen Pharmaceuticals; Inc.

发明人:

Sébastien Rocchi,Chantal Devin,Wei Tian,Martin Bohlin

申请号：

US15205909

公开号：

US10125165B2

申请日:

2016.07.08

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present disclosure relates to methods of preparing and crystallizing β-turn cyclic peptidomimetic salts of formula I:where R1, R2, R3, R4, R5, R6, R7, R8, R10, X, Y and n are as defined in the specification.The present disclosure provides a more efficient route for preparing a crystalline form of β-turn cyclic peptidomimetic compounds and salts thereof.

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