Amitabha Chaudhuri,Ravi Gupta,Priyanka Shah,Malini Manoharan,Kiran V. Paul,Rohit Gupta
申请号:
US15791301
公开号:
US10350280B2
申请日:
2017.10.23
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention describes a method for identifying T-cell activating neo-epitopes from all genetically altered proteins. The mutated proteins contribute to neo-epitopes after they are proteolytically degraded within antigen presenting cells, such as dendritic cells and macrophages.